{"product_id":"new-product-580253","title":"Rad51(Phospho Thr309) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe RAD51(PHOSPHO THR309) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of RAD51 protein phosphorylated at threonine 309. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eRAD51 is a crucial protein involved in DNA repair and recombination processes. Phosphorylation of RAD51 at threonine 309 has been shown to regulate its activity and function, making it an important target for research in the field of DNA repair and cancer biology. This polyclonal antibody specifically recognizes the phosphorylated form of RAD51 at threonine 309, enabling precise investigation of its role in cellular processes.\u003cbr\u003e\u003cbr\u003eThe RAD51(PHOSPHO THR309) Polyclonal Antibody exhibits outstanding performance in various experimental conditions, displaying high sensitivity and specificity. It has been extensively validated using a wide range of cell lines and tissues, ensuring reliable and reproducible results. The antibody demonstrates minimal cross-reactivity with non-phosphorylated RAD51, ensuring accurate detection and analysis of the phosphorylated form.\u003cbr\u003e\u003cbr\u003eWith its exceptional quality and reliability, the RAD51(PHOSPHO THR309) Polyclonal Antibody is an indispensable tool for researchers studying DNA repair mechanisms, cancer biology, and related fields. Its superior performance and specificity make it an ideal choice for precise and accurate detection of phosphorylated RAD51 at threonine 309, facilitating in-depth investigations and advancing scientific knowledge in these areas.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547911012632,"sku":"BT-AP13509","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_fa3e3f66-eefd-4bb4-a882-4b0eaf147305.png?v=1705689537","url":"https:\/\/danabiosci.com\/products\/new-product-580253","provider":"Dana Bioscience","version":"1.0","type":"link"}