{"product_id":"new-product-580217","title":"PYK2(Phospho Tyr402) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity t\u003c\/p\u003e\n\u003cp\u003eIntroducing the PYK2 Phospho-Tyr402 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of biotechnology. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of PYK2 at tyrosine 402 residue, enabling researchers to delve deeper into the intricate world of cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision and expertise, the PYK2 Phospho-Tyr402 Polyclonal Antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity towards the phosphorylated form of PYK2 guarantees minimal cross-reactivity, thereby enhancing the credibility of experimental outcomes.\u003cbr\u003e\u003cbr\u003eThis antibody is an invaluable tool for scientists and researchers engaged in the study of cellular signaling cascades, as it enables the investigation of PYK2 activation and its subsequent downstream effects. By targeting the phosphorylation site at tyrosine 402, this antibody facilitates the elucidation of PYK2-mediated signaling events, shedding light on its role in various physiological and pathological processes.\u003cbr\u003e\u003cbr\u003eThe PYK2 Phospho-Tyr402 Polyclonal Antibody is meticulously validated through rigorous quality control measures, ensuring its superior performance and reproducibility. Its exceptional sensitivity allows for the detection of even low levels of phosphorylated PYK2, enabling researchers to explore subtle changes in cellular signaling dynamics.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody is compatible with a wide range of experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence, providing researchers with the flexibility to employ diverse methodologies in their investigations. Its versatility and reliability make it an indispensable asset in the pursuit of scientific breakthroughs.\u003cbr\u003e\u003cbr\u003eIn summary, the PYK2 Phospho-Tyr402 Polyclonal Antibody by BT Lab is a state-of-the-art research tool that empowers scientists to unravel the complexities of cellular signaling pathways. With its exceptional sensitivity, specificity, and compatibility with various experimental techniques, this antibody is poised to revolutionize the field of cellular signaling research. Trust in BT Lab's commitment to excellence and elevate your research endeavors with the PYK2 Phospho-Tyr402 Polyclonal Antibody.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547875590424,"sku":"BT-AP13420","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a8f56efc-3069-4a20-ae0d-ac6b521017b4.png?v=1705689324","url":"https:\/\/danabiosci.com\/products\/new-product-580217","provider":"Dana Bioscience","version":"1.0","type":"link"}