{"product_id":"new-product-580103","title":"PLXB1 Polyclonal Antibody","description":"\u003cp\u003edisease:Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM:Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:Proteolytic processing favors heterodimerization with PLXNB2 and SEMA4D binding.,Belongs to the plexin family.,Contains 1 Sema domain.,Contains 3 IPT\/TIG domains.,subunit:Monomer, and heterodimer with PLXNB2 after proteolytic processing. Binds RAC1 that has been activated by GTP binding. Interaction with SEMA4D promotes binding of cytoplasmic ligands. Binds PLXNA1 (By similarity). Binds ARHGEF11, ARHGEF12, ERBB2, MET, MST1R, RND1, NRP1 and NRP2.,tissue specificity:Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.,\u003c\/p\u003e\n\u003cp\u003eIntroducing the PLXB1 Polyclonal Antibody, meticulously developed by BT Lab in collaboration with Dana Biosciences. This cutting-edge product is designed to revolutionize the field of biomedical research, offering unparalleled accuracy and reliability in detecting PLXB1 protein expression.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision, the PLXB1 Polyclonal Antibody exhibits exceptional specificity, enabling researchers to confidently investigate the intricate mechanisms associated with PLXB1. Its high affinity ensures minimal cross-reactivity, guaranteeing accurate and reproducible results in a wide range of applications.\u003cbr\u003e\u003cbr\u003eThe PLXB1 Polyclonal Antibody boasts an advanced formulation, meticulously optimized to deliver superior performance. Its exceptional sensitivity allows for the detection of even the lowest levels of PLXB1 expression, facilitating comprehensive analysis and enhancing the understanding of its biological functions.\u003cbr\u003e\u003cbr\u003eWith a robust and versatile design, this antibody is compatible with various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. Its adaptability empowers researchers to explore PLXB1 expression in diverse biological samples, facilitating comprehensive investigations across multiple research domains.\u003cbr\u003e\u003cbr\u003eFurthermore, the PLXB1 Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control measures to ensure utmost reliability and consistency. Each batch is meticulously tested to meet the highest industry standards, guaranteeing optimal performance and reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the PLXB1 Polyclonal Antibody by BT Lab, in collaboration with Dana Biosciences, represents a breakthrough in the field of biomedical research. Its exceptional specificity, sensitivity, and versatility make it an indispensable tool for scientists and researchers striving to unravel the complexities of PLXB1 protein expression. Trust in this meticulously crafted antibody to elevate your research endeavors and pave the way for groundbreaking discoveries.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547772141848,"sku":"BT-AP13192","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_71bdba24-2769-4d8c-9dbb-936a79b48cdd.png?v=1705688718","url":"https:\/\/danabiosci.com\/products\/new-product-580103","provider":"Dana Bioscience","version":"1.0","type":"link"}