{"product_id":"new-product-579971","title":"PDK1(Phospho Tyr9) Polyclonal Antibody","description":"\u003cp\u003eCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB\/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM:Phosphorylated on tyrosine and serine\/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241, leading to its own activation.,Belongs to the protein kinase superfamily.,Belongs to the protein kinase superfamily. AGC Ser\/Thr protein kinase family. PDK1 subfamily.,Contains 1 PH domain.,Contains 1 protein kinase domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.,subunit:Interacts with TUSC4.,tissue specificity:Appears to be expressed ubiquitously.,\u003c\/p\u003e\n\u003cp\u003eThe PDK1(Phospho Tyr9) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PDK1 protein phosphorylated at Tyr9 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein. \u003cbr\u003e\u003cbr\u003ePDK1, also known as 3-phosphoinositide-dependent protein kinase 1, plays a crucial role in various cellular processes, including cell growth, proliferation, and survival. The phosphorylation of PDK1 at Tyr9 residue is known to regulate its activity and downstream signaling pathways. \u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated PDK1 protein in complex biological samples. \u003cbr\u003e\u003cbr\u003eThe PDK1(Phospho Tyr9) Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing wastage. \u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, this antibody is an indispensable tool for researchers and scientists studying PDK1 signaling pathways and its role in various physiological and pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547653488920,"sku":"BT-AP12901","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_6f4727fc-364a-4d47-8f43-5c0e6fb9a787.png?v=1705688064","url":"https:\/\/danabiosci.com\/products\/new-product-579971","provider":"Dana Bioscience","version":"1.0","type":"link"}