{"product_id":"new-product-579934","title":"PCBP2 Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate\u003c\/p\u003e\n\u003cp\u003eThe PCBP2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of PCBP2 protein expression in various biological samples. This antibody has been extensively validated for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.\u003cbr\u003e\u003cbr\u003ePCBP2, also known as poly(rC)-binding protein 2, is a multifunctional RNA-binding protein that plays a crucial role in post-transcriptional regulation of gene expression. It is involved in various cellular processes, including mRNA stability, translation, and alternative splicing. Dysregulation of PCBP2 has been implicated in the pathogenesis of several diseases, including cancer and neurodegenerative disorders.\u003cbr\u003e\u003cbr\u003eThe PCBP2 Polyclonal Antibody has been developed using high-quality immunogens and state-of-the-art production techniques to ensure exceptional specificity and sensitivity. It exhibits minimal cross-reactivity with other related proteins, thereby enabling accurate and reliable detection of PCBP2 in complex biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody demonstrates excellent performance in IHC, allowing for the visualization and localization of PCBP2 protein in tissue sections. It produces clear and distinct staining patterns, facilitating the identification of PCBP2 expression in specific cell types or subcellular compartments.\u003cbr\u003e\u003cbr\u003eFurthermore, the PCBP2 Polyclonal Antibody is highly suitable for IF applications, enabling the visualization of PCBP2 protein in fixed cells or tissues. It provides bright and specific staining, allowing for the precise examination of PCBP2 localization and dynamics within the cellular context.\u003cbr\u003e\u003cbr\u003eIn addition, this antibody is compatible with WB analysis, enabling the detection and quantification of PCBP2 protein levels in cell lysates or tissue extracts. It exhibits strong and specific band signals, ensuring accurate measurement of PCBP2 expression levels.\u003cbr\u003e\u003cbr\u003eThe PCBP2 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes rigorous quality control procedures to ensure consistent and reliable performance.\u003cbr\u003e\u003cbr\u003eIn summary, the PCBP2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of PCBP2 protein expression. Its exceptional performance in IHC, IF, and WB applications makes it an invaluable asset for researchers studying the role of PCBP2 in various biological processes and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547591983384,"sku":"BT-AP12842","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c904ba16-341c-4e5a-a267-ed70fd2c60f9.png?v=1705687841","url":"https:\/\/danabiosci.com\/products\/new-product-579934","provider":"Dana Bioscience","version":"1.0","type":"link"}