{"product_id":"new-product-579886","title":"PAK gamma(Phospho Ser141) Polyclonal Antibody","description":"\u003cp\u003eThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine\/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.\u003c\/p\u003e\n\u003cp\u003eThe PAK gamma (Phospho Ser141) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of PAK gamma protein phosphorylated at Ser141. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003ePAK gamma, a member of the p21-activated kinase (PAK) family, plays a crucial role in various cellular processes, including cell proliferation, migration, and cytoskeletal reorganization. Phosphorylation of PAK gamma at Ser141 has been implicated in the regulation of its activity and downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThe PAK gamma (Phospho Ser141) Polyclonal Antibody has been developed using state-of-the-art techniques and high-quality materials to ensure optimal performance and reliability. It exhibits high specificity towards the phosphorylated form of PAK gamma at Ser141, with minimal cross-reactivity to other proteins.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, making it easy to handle and use. It is provided in a convenient size, allowing for multiple experiments and minimizing wastage. The antibody has been validated for use in a variety of sample types, including cell lysates, tissue lysates, and whole-cell extracts.\u003cbr\u003e\u003cbr\u003eWhen used in Western blotting, the PAK gamma (Phospho Ser141) Polyclonal Antibody shows a strong and specific signal at the expected molecular weight of phosphorylated PAK gamma. It can be used for both qualitative and quantitative analysis of PAK gamma phosphorylation levels.\u003cbr\u003e\u003cbr\u003eIn immunohistochemistry and immunofluorescence applications, this antibody exhibits excellent staining patterns, enabling the visualization and localization of phosphorylated PAK gamma within cells and tissues. It can be used in combination with various detection methods, such as chromogenic or fluorescent substrates, to achieve optimal results.\u003cbr\u003e\u003cbr\u003eOverall, the PAK gamma (Phospho Ser141) Polyclonal Antibody is a reliable and versatile tool for researchers studying the role of PAK gamma phosphorylation in cellular processes. Its high specificity, sensitivity, and ease of use make it an essential component of any laboratory working in the field of cell biology and signal transduction.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547506688280,"sku":"BT-AP12757","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e2ea9ec7-5a44-4949-b05b-7a28f649e6b8.png?v=1705687613","url":"https:\/\/danabiosci.com\/products\/new-product-579886","provider":"Dana Bioscience","version":"1.0","type":"link"}