{"product_id":"new-product-579870","title":"PABP4 Polyclonal Antibody","description":"\u003cp\u003ePoly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript va\u003c\/p\u003e\n\u003cp\u003eThe PABP4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PABP4 protein in various biological samples. This antibody is produced using state-of-the-art technology and has been rigorously validated to ensure its reliability and accuracy.\u003cbr\u003e\u003cbr\u003ePABP4, also known as Poly(A)-binding protein 4, is a crucial protein involved in the regulation of mRNA stability and translation. It plays a vital role in post-transcriptional gene expression and is implicated in various cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of PABP4 has been associated with several diseases, making it an important target for research and diagnostic purposes.\u003cbr\u003e\u003cbr\u003eThe PABP4 Polyclonal Antibody exhibits exceptional specificity towards PABP4 protein, enabling precise detection and quantification in a wide range of sample types, including cell lysates, tissue homogenates, and biological fluids. It recognizes both endogenous and recombinant PABP4 protein, ensuring versatility in experimental applications.\u003cbr\u003e\u003cbr\u003eThis antibody demonstrates high sensitivity, allowing for the detection of low-abundance PABP4 protein levels. Its superior performance is attributed to the advanced purification techniques employed during its production, resulting in a highly purified and concentrated antibody preparation.\u003cbr\u003e\u003cbr\u003eThe PABP4 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and format, ensuring ease of handling and storage. The antibody is stable under recommended storage conditions, preserving its functionality and performance over an extended period.\u003cbr\u003e\u003cbr\u003eIn summary, the PABP4 Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of PABP4 protein. Its exceptional specificity, sensitivity, and stability make it an invaluable asset for researchers and clinicians working in the fields of molecular biology, biochemistry, and diagnostics.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547471462680,"sku":"BT-AP12724","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_3626fbec-dbb8-426c-8ef4-6bec6978ffd9.png?v=1705687527","url":"https:\/\/danabiosci.com\/products\/new-product-579870","provider":"Dana Bioscience","version":"1.0","type":"link"}