{"product_id":"new-product-579850","title":"p63(Phospho Ser395) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem\/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip\/palate syndrome 3 (EEC3); split-hand\/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip\/palate; ADULT syndrome (acro-dermato-ungual-lacrim\u003c\/p\u003e\n\u003cp\u003eThe p63(Phospho Ser395) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of p63 protein phosphorylated at Serine 395. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe p63 protein is a member of the p53 family and plays a crucial role in the regulation of cell proliferation, differentiation, and apoptosis. Phosphorylation of p63 at Serine 395 has been implicated in the modulation of its transcriptional activity and downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been developed using state-of-the-art techniques and exhibits exceptional specificity and sensitivity. It has been extensively tested and validated to ensure reliable and reproducible results. The antibody recognizes the phosphorylated form of p63 at Serine 395 with high affinity, while exhibiting minimal cross-reactivity with non-phosphorylated p63 or other related proteins.\u003cbr\u003e\u003cbr\u003eThe p63(Phospho Ser395) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the p63(Phospho Ser395) Polyclonal Antibody is an indispensable tool for researchers studying the role of p63 phosphorylation in various biological processes. Its versatility and high specificity make it suitable for a wide range of applications, enabling researchers to gain valuable insights into the molecular mechanisms underlying cellular processes.\u003cbr\u003e\u003cbr\u003eOrder your p63(Phospho Ser395) Polyclonal Antibody today and unlock the potential of p63 phosphorylation research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547428274456,"sku":"BT-AP12688","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_36a7a857-dc55-4718-98c9-2c906c45cd5c.png?v=1705687404","url":"https:\/\/danabiosci.com\/products\/new-product-579850","provider":"Dana Bioscience","version":"1.0","type":"link"}