{"product_id":"new-product-579821","title":"p38(Phospho Tyr323) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1\/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d\u003c\/p\u003e\n\u003cp\u003eThe p38(Phospho Tyr323) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of p38 protein phosphorylated at Tyr323. This antibody has been rigorously validated and exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.\u003cbr\u003e\u003cbr\u003eThe p38 protein, a member of the mitogen-activated protein kinase (MAPK) family, plays a crucial role in cellular responses to stress and inflammation. Phosphorylation of p38 at Tyr323 has been implicated in the regulation of various cellular processes, including cell proliferation, differentiation, and apoptosis.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been meticulously developed using state-of-the-art techniques and high-quality materials to ensure optimal specificity and sensitivity. It has been extensively tested against a wide range of samples, including human, mouse, and rat tissues, and has consistently demonstrated excellent performance.\u003cbr\u003e\u003cbr\u003eThe p38(Phospho Tyr323) Polyclonal Antibody offers several advantages over other commercially available antibodies. Its high affinity and specificity enable accurate and reliable detection of phosphorylated p38 protein, even at low expression levels. Additionally, it exhibits minimal cross-reactivity with non-phosphorylated p38 protein, ensuring precise and specific results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone reconstitution steps. The antibody is also compatible with a variety of commonly used detection systems, allowing for seamless integration into existing experimental protocols.\u003cbr\u003e\u003cbr\u003eIn summary, the p38(Phospho Tyr323) Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of phosphorylated p38 protein. Its exceptional performance, specificity, and ease of use make it an invaluable asset for researchers studying cellular signaling pathways and investigating the role of p38 in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47547372863768,"sku":"BT-AP12640","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_06584a32-40c2-47e6-96ee-d8725fd2971f.png?v=1705687259","url":"https:\/\/danabiosci.com\/products\/new-product-579821","provider":"Dana Bioscience","version":"1.0","type":"link"}