{"product_id":"new-product-579368","title":"NACA(Phospho Ser43) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.\u003c\/p\u003e\n\u003cp\u003eThe NACA(Phospho Ser43) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NACA protein phosphorylated at Serine 43. This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe NACA protein plays a crucial role in cellular processes such as DNA repair, transcriptional regulation, and chromatin remodeling. Phosphorylation of NACA at Serine 43 has been implicated in the modulation of its function and interaction with other proteins. Therefore, the ability to accurately measure the phosphorylation status of NACA is of utmost importance in understanding its role in cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eOur NACA(Phospho Ser43) Polyclonal Antibody has been developed using state-of-the-art techniques to ensure high specificity and sensitivity. It has been extensively tested against a wide range of samples, including human, mouse, and rat tissues, to guarantee reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits exceptional performance in Western blotting, providing clear and distinct bands at the expected molecular weight of NACA protein phosphorylated at Serine 43. It also demonstrates excellent staining patterns in immunohistochemistry and immunofluorescence, enabling precise localization of the phosphorylated NACA protein within cells and tissues.\u003cbr\u003e\u003cbr\u003eFurthermore, the NACA(Phospho Ser43) Polyclonal Antibody has been validated for its compatibility with various secondary detection systems, making it a versatile tool for researchers in diverse fields of study.\u003cbr\u003e\u003cbr\u003eIn summary, the NACA(Phospho Ser43) Polyclonal Antibody is a reliable and highly specific reagent that enables accurate detection and quantification of NACA protein phosphorylated at Serine 43. Its exceptional performance in multiple applications makes it an invaluable tool for researchers investigating the role of NACA in cellular processes and signaling pathways.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546989969688,"sku":"BT-AP11689","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_0caa57e6-b106-4fe7-967c-ae8d413d43fb.png?v=1705684960","url":"https:\/\/danabiosci.com\/products\/new-product-579368","provider":"Dana Bioscience","version":"1.0","type":"link"}