{"product_id":"new-product-579316","title":"MuSK(Phospho Tyr755) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.\u003c\/p\u003e\n\u003cp\u003eThe MuSK (Phospho Tyr755) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of MuSK protein phosphorylated at tyrosine 755. This antibody is produced using a polyclonal approach, ensuring a diverse range of antibodies that recognize different epitopes on the target protein. \u003cbr\u003e\u003cbr\u003eMuSK, or Muscle-Specific Kinase, is a key regulator of neuromuscular junction formation and maintenance. Phosphorylation of MuSK at tyrosine 755 is crucial for its activation and subsequent signaling cascades that contribute to the development and function of the neuromuscular junction. Therefore, the ability to specifically detect and quantify phosphorylated MuSK at this site is of great importance in understanding the molecular mechanisms underlying neuromuscular disorders and diseases.\u003cbr\u003e\u003cbr\u003eThe MuSK (Phospho Tyr755) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated MuSK and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use in various applications, including but not limited to, protein expression analysis, protein-protein interaction studies, and cellular localization studies. It is recommended to use this antibody at a dilution range of 1:1000 to 1:5000 for optimal results.\u003cbr\u003e\u003cbr\u003eIn summary, the MuSK (Phospho Tyr755) Polyclonal Antibody is a valuable tool for researchers and scientists working in the field of neuromuscular biology. Its high specificity, sensitivity, and versatility make it an essential component in elucidating the intricate molecular mechanisms underlying neuromuscular disorders and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546966507800,"sku":"BT-AP11590","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_556bc9e4-6b05-48f0-b611-869cd44c3586.png?v=1705684676","url":"https:\/\/danabiosci.com\/products\/new-product-579316","provider":"Dana Bioscience","version":"1.0","type":"link"}