{"product_id":"new-product-579313","title":"Mucin 1(Phospho Ser1227) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp\u003c\/p\u003e\n\u003cp\u003eThe Mucin 1 (Phospho Ser1227) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of Mucin 1 protein phosphorylated at Ser1227. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eMucin 1 is a transmembrane glycoprotein that plays a crucial role in cell adhesion, signaling, and protection of epithelial surfaces. Phosphorylation of Mucin 1 at Ser1227 has been implicated in various cellular processes, including cell proliferation, migration, and invasion. Therefore, the ability to accurately measure the phosphorylation status of Mucin 1 at Ser1227 is of great importance in understanding its functional significance in normal and pathological conditions.\u003cbr\u003e\u003cbr\u003eThe Mucin 1 (Phospho Ser1227) Polyclonal Antibody has been developed using high-quality immunogens and state-of-the-art production techniques to ensure optimal specificity and sensitivity. It exhibits minimal cross-reactivity with non-phosphorylated Mucin 1 and other related proteins, thereby providing reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It has been extensively tested and validated in various experimental conditions to ensure consistent and reproducible results. Additionally, it is compatible with a wide range of sample types, including cell lysates, tissue extracts, and cultured cells.\u003cbr\u003e\u003cbr\u003eIn summary, the Mucin 1 (Phospho Ser1227) Polyclonal Antibody is a valuable tool for researchers studying the phosphorylation status of Mucin 1 at Ser1227. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications in both basic and clinical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546965819672,"sku":"BT-AP11579","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f1f9161f-e278-4227-95a4-76ed38ccf2dd.png?v=1705684663","url":"https:\/\/danabiosci.com\/products\/new-product-579313","provider":"Dana Bioscience","version":"1.0","type":"link"}