{"product_id":"new-product-579281","title":"MRCKG Polyclonal Antibody","description":"\u003cp\u003eCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Maintained in an inactive, closed conformation by an interaction between the kinase domain and the negative autoregulatory C-terminal coiled-coil region. Agonist binding to the phorbol ester binding site disrupts this, releasing the kinase domain to allow N-terminus-mediated dimerization and kinase activation by transautophosphorylation.,May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.,Belongs to the protein kinase superfamily. AGC Ser\/Thr protein kinase family. DMPK subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 CNH domain.,Contains 1 CRIB domain.,Contains 1 PH domain.,Contains 1 phorbol-ester\/DAG-type zinc finger.,Contains 1 protein kinase domain.,subcellular location:Concentrates at the leading edge of cells.,subunit:Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42.,tissue specificity:Expressed in heart and skeletal muscle.,\u003c\/p\u003e\n\u003cp\u003eThe MRCKG Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of MRCKG protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe MRCKG Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the precise identification and quantification of MRCKG protein levels in complex biological samples. Its high affinity and selectivity towards MRCKG make it an ideal choice for researchers and scientists studying the role and function of this protein in various cellular processes.\u003cbr\u003e\u003cbr\u003eThis antibody has been rigorously tested and validated to ensure consistent and reproducible results. Its outstanding performance is attributed to its superior quality and purity, which are achieved through a stringent purification process. The MRCKG Polyclonal Antibody is manufactured using state-of-the-art techniques and adheres to the highest industry standards, guaranteeing optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life ensures that researchers can rely on its performance for an extended period, eliminating the need for frequent reordering and reducing experimental variability.\u003cbr\u003e\u003cbr\u003eIn summary, the MRCKG Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of MRCKG protein expression. Its exceptional sensitivity, specificity, and performance make it an invaluable asset for researchers and scientists in their quest to unravel the complexities of MRCKG and its involvement in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546943897880,"sku":"BT-AP11464","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e62bd058-2fed-4dea-9078-8eb485ac7c92.png?v=1705684499","url":"https:\/\/danabiosci.com\/products\/new-product-579281","provider":"Dana Bioscience","version":"1.0","type":"link"}