{"product_id":"new-product-579241","title":"MLL Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe MLL Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the MLL protein in a variety of biological samples. This antibody has been extensively validated for use in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe MLL protein is a key regulator of gene expression and is involved in a variety of cellular processes, including cell differentiation and proliferation. Dysregulation of the MLL protein has been implicated in a number of diseases, including leukemia and other cancers.\u003cbr\u003e\u003cbr\u003eThe MLL Polyclonal Antibody has been produced using state-of-the-art techniques and is of the highest quality. It has been rigorously tested to ensure that it is specific to the MLL protein and does not cross-react with other proteins.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient format and is ready to use in a variety of applications. It has been optimized for use with a range of detection systems and is compatible with a variety of sample types, including tissue lysates, cell lysates, and purified proteins.\u003cbr\u003e\u003cbr\u003eOverall, the MLL Polyclonal Antibody is an essential tool for researchers studying the MLL protein and its role in disease. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its quality and reliability ensure that it will provide accurate and reproducible results.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546916929816,"sku":"BT-AP11380","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_b7e0dccd-8cab-4b49-8110-7be53d50f0af.png?v=1705684303","url":"https:\/\/danabiosci.com\/products\/new-product-579241","provider":"Dana Bioscience","version":"1.0","type":"link"}