{"product_id":"new-product-579158","title":"MeCP2 Polyclonal Antibody","description":"\u003cp\u003eDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Alternative splicing results in multiple transcript variants encoding different isofor\u003c\/p\u003e\n\u003cp\u003eThe MeCP2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MeCP2 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe MeCP2 Polyclonal Antibody is a valuable tool for researchers studying the role of MeCP2 in various biological processes, including gene expression, chromatin remodeling, and neuronal development. This antibody has been extensively tested and validated for its specificity and sensitivity, ensuring accurate and reliable results in a variety of experimental settings.\u003cbr\u003e\u003cbr\u003eWith its high specificity and sensitivity, the MeCP2 Polyclonal Antibody is an essential tool for researchers studying the complex mechanisms of gene regulation and neuronal development. Whether you are studying the role of MeCP2 in neurodevelopmental disorders or investigating the molecular mechanisms of gene expression, this antibody is an indispensable tool for your research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546855063832,"sku":"BT-AP11209","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c50bc165-c2a6-4b98-a3ac-2d1a184d31a9.png?v=1705683877","url":"https:\/\/danabiosci.com\/products\/new-product-579158","provider":"Dana Bioscience","version":"1.0","type":"link"}