{"product_id":"new-product-579106","title":"MAML2 Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the Mastermind-like family of proteins. All family members are proline and glutamine-rich, and contain a conserved basic domain that binds the ankyrin repeat domain of the intracellular domain of the Notch receptors (ICN1-4) in their N-terminus, and a transcriptional activation domain in their C-terminus. This protein binds to an extended groove that is formed by the interaction of CBF1, Suppressor of Hairless, LAG-1 (CSL) with ICN, and positively regulates Notch signaling. High levels of expression of this gene have been observed in several B cell-derived lymphomas. Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas, while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL). Copy number variation in the p\u003c\/p\u003e\n\u003cp\u003eThe MAML2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the Mastermind-like protein 2 (MAML2). This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for MAML2.\u003cbr\u003e\u003cbr\u003eThe Mastermind-like protein 2 (MAML2) is a transcriptional coactivator that plays a crucial role in various cellular processes, including gene expression regulation and cell differentiation. Dysregulation of MAML2 has been implicated in several diseases, making it an important target for research and diagnostic purposes.\u003cbr\u003e\u003cbr\u003eThe MAML2 Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of MAML2 in various sample types.\u003cbr\u003e\u003cbr\u003eThis antibody is manufactured using high-quality materials and state-of-the-art techniques, ensuring consistent and reproducible results. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the MAML2 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in studying MAML2 and its associated biological processes. Its high specificity and sensitivity make it an ideal choice for investigating MAML2 expression patterns, protein-protein interactions, and potential therapeutic targets.\u003cbr\u003e\u003cbr\u003eChoose the MAML2 Polyclonal Antibody for accurate and reliable detection of MAML2 in your research and diagnostic applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546800800024,"sku":"BT-AP11089","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_179e6fdf-26b3-4add-bca6-3a8f5f7695de.png?v=1705683539","url":"https:\/\/danabiosci.com\/products\/new-product-579106","provider":"Dana Bioscience","version":"1.0","type":"link"}