{"product_id":"new-product-579016","title":"LKB1(Phospho Thr189) Polyclonal Antibody","description":"\u003cp\u003eThis gene, which encodes a member of the serine\/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.\u003c\/p\u003e\n\u003cp\u003eThe LKB1(Phospho Thr189) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of LKB1 protein phosphorylated at threonine 189. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the phosphorylated form of LKB1.\u003cbr\u003e\u003cbr\u003eLKB1, also known as liver kinase B1, is a serine\/threonine kinase that plays a crucial role in various cellular processes, including cell growth, metabolism, and polarity. Phosphorylation of LKB1 at threonine 189 has been implicated in the regulation of its activity and downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThe LKB1(Phospho Thr189) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated LKB1 and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use in various applications, including protein expression analysis, cellular localization studies, and functional assays. It is compatible with multiple detection methods, such as chemiluminescence, fluorescence, and colorimetric detection.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the LKB1(Phospho Thr189) Polyclonal Antibody is an indispensable tool for researchers and scientists studying LKB1 signaling pathways and its role in various physiological and pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546738114840,"sku":"BT-AP10934","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a51e0f8a-1780-4cb2-bab2-2aca79c8b6b7.png?v=1705683109","url":"https:\/\/danabiosci.com\/products\/new-product-579016","provider":"Dana Bioscience","version":"1.0","type":"link"}