{"product_id":"new-product-578962","title":"LAP2B Polyclonal Antibody","description":"\u003cp\u003ealternative products:Additional isoforms seem to exist,Has two structurally independent, non-interacting domains: LEM-like (also called LAP2-N or LEM-D) and LEM (also called LAP2-C or LEM-B). LEM-like binds DNA while LEM interacts with BANF1.,May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Play an important role, together with LMNA, in the nuclear anchorage of RB1.,May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95.,TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.,pharmaceutical:TP5 is available under the names Timunox (Cilag), Sintomodulina (Italofarmaco) and Mepentil (Recordati). Used in primary and secondary immune deficiencies, autoimmunity, infections and cancer.,PTM:Mitosis-specific phosphorylation specifically abolishes its binding to lamin B and chromosomes.,PTM:Phosphorylated in a mitose-specific manner.,Belongs to the LEM family.,Contains 1 LEM domain.,Contains 1 LEM-like domain.,subcellular location:Expressed diffusely throughout the nucleus.,subcellular location:Tightly associated with the nuclear lamina.,subunit:Interacts with LMNA, BANF1 and RB1 and with chromosomes. Associates directly or indirectly with lamins at specific cell-cycle stages.,subunit:Interacts with LMNB1, LMNB2, BANF1, NAKAP95, GMCL and chromosomes.,tissue specificity:Expressed in many tissues. Most abundant in adult thymus and fetal liver.,\u003c\/p\u003e\n\u003cp\u003eThe LAP2B Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of LAP2B protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.\u003cbr\u003e\u003cbr\u003eThe LAP2B Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other proteins to ensure its specificity for LAP2B. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eWith its superior performance characteristics, the LAP2B Polyclonal Antibody is an invaluable tool for researchers studying the role of LAP2B in cellular processes and disease mechanisms. Its high affinity and sensitivity enable the detection of even low levels of LAP2B expression, providing valuable insights into its function and regulation.\u003cbr\u003e\u003cbr\u003eThe LAP2B Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is available in different sizes to accommodate various experimental needs. Each batch is accompanied by detailed documentation, including quality control data and recommended protocols, ensuring optimal performance and reproducibility.\u003cbr\u003e\u003cbr\u003eChoose the LAP2B Polyclonal Antibody for its exceptional quality, reliability, and performance, and unlock new possibilities in your research endeavors.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546668876056,"sku":"BT-AP10836","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d7389f80-cab3-4c93-8376-c423015ce236.png?v=1705682530","url":"https:\/\/danabiosci.com\/products\/new-product-578962","provider":"Dana Bioscience","version":"1.0","type":"link"}