{"product_id":"new-product-578953","title":"KV2.1(Phospho Ser805) Polyclonal Antibody","description":"\u003cp\u003eVoltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.\u003c\/p\u003e\n\u003cp\u003eThe KV2.1(Phospho Ser805) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of the phosphorylated form of the KV2.1 protein at Ser805 residue. This antibody has been meticulously developed and rigorously validated to ensure its reliability and accuracy in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe KV2.1 protein, a member of the voltage-gated potassium channel family, plays a crucial role in regulating neuronal excitability and action potential duration. Phosphorylation of the KV2.1 protein at Ser805 has been implicated in modulating its function and cellular localization. Therefore, the ability to specifically detect and measure the phosphorylated form of KV2.1 at this site is of utmost importance in understanding the intricate mechanisms underlying neuronal signaling and synaptic plasticity.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been generated using high-quality immunogens and state-of-the-art immunization techniques, resulting in a highly specific and sensitive reagent. It exhibits minimal cross-reactivity with non-phosphorylated KV2.1 protein and other related potassium channels, ensuring accurate and reliable results. The antibody has been extensively validated using both in vitro and in vivo models, demonstrating its specificity and sensitivity in detecting the phosphorylated form of KV2.1 at Ser805.\u003cbr\u003e\u003cbr\u003eThe KV2.1(Phospho Ser805) Polyclonal Antibody offers exceptional versatility and can be used in a wide range of experimental settings. Its compatibility with various techniques, such as Western blotting, immunoprecipitation, and immunofluorescence, allows for comprehensive analysis of the phosphorylation status of KV2.1 in different cell types and tissues. Furthermore, its robust performance in both qualitative and quantitative assays ensures accurate and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the KV2.1(Phospho Ser805) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of the phosphorylated form of the KV2.1 protein at Ser805 residue. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers studying neuronal signaling, synaptic plasticity, and potassium channel function.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546663141656,"sku":"BT-AP10796","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_fb5aeac2-d620-48d7-b033-842cdd018f19.png?v=1705682472","url":"https:\/\/danabiosci.com\/products\/new-product-578953","provider":"Dana Bioscience","version":"1.0","type":"link"}