{"product_id":"new-product-578951","title":"Kv11.3 Polyclonal Antibody","description":"\u003cp\u003eVoltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.\u003c\/p\u003e\n\u003cp\u003eThe Kv11.3 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Kv11.3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Kv11.3 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity by various assays, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Kv11.3 protein, also known as ether-a-go-go-related gene 3 (ERG3), is a member of the voltage-gated potassium channel family and plays a crucial role in regulating the electrical activity of cells. Dysregulation of Kv11.3 has been implicated in various diseases, including cardiac arrhythmias, epilepsy, and cancer. Therefore, the Kv11.3 Polyclonal Antibody is a valuable tool for researchers studying the function and regulation of Kv11.3 in normal and pathological conditions.\u003cbr\u003e\u003cbr\u003eThe Kv11.3 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is available in various sizes and formats, including 50 µg, 100 µg, and 200 µg sizes, as well as conjugated forms such as biotin, FITC, and HRP. This antibody has been extensively tested and validated for its performance and quality, ensuring reliable and reproducible results in various applications.\u003cbr\u003e\u003cbr\u003eIn summary, the Kv11.3 Polyclonal Antibody is a high-quality and reliable antibody that provides specific and sensitive detection of Kv11.3 protein in various biological samples. It is an essential tool for researchers studying the function and regulation of Kv11.3 in normal and pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546662158616,"sku":"BT-AP10794","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_1e2f7744-9f54-4463-bb87-08d7e0706560.png?v=1705682463","url":"https:\/\/danabiosci.com\/products\/new-product-578951","provider":"Dana Bioscience","version":"1.0","type":"link"}