{"product_id":"new-product-578812","title":"JDP2(Phospho Thr148) Polyclonal Antibody","description":"\u003cp\u003eComponent of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3\/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.,Belongs to the bZIP family. ATF subfamily.,Contains 1 bZIP domain.,subunit:Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.,\u003c\/p\u003e\n\u003cp\u003eThe JDP2(Phospho Thr148) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of JDP2 protein phosphorylated at threonine 148. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe JDP2 protein, also known as Jun dimerization protein 2, plays a crucial role in various cellular processes, including gene expression regulation, cell proliferation, and differentiation. Phosphorylation of JDP2 at threonine 148 has been implicated in the modulation of its activity and function.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is raised in rabbits using a synthetic phospho-peptide corresponding to the phosphorylated threonine 148 region of JDP2. It exhibits high affinity and specificity towards the phosphorylated form of JDP2, enabling accurate detection and quantification in various experimental settings.\u003cbr\u003e\u003cbr\u003eThe JDP2(Phospho Thr148) Polyclonal Antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in multiple species, ensuring its versatility and applicability in diverse research areas.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity and specificity, this antibody offers researchers a valuable tool for investigating the role of JDP2 phosphorylation in cellular processes and disease mechanisms. Its reliable performance and reproducibility make it an indispensable asset for any laboratory conducting research in the field of molecular biology and cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eOrder the JDP2(Phospho Thr148) Polyclonal Antibody today and unlock new insights into the intricate mechanisms governing cellular function and disease progression.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546559594776,"sku":"BT-AP10570","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_622d5aa0-e048-4231-a0c4-e074d7d651fb.png?v=1705681679","url":"https:\/\/danabiosci.com\/products\/new-product-578812","provider":"Dana Bioscience","version":"1.0","type":"link"}