{"product_id":"new-product-578582","title":"HNF4-alpha(Phospho Ser313) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe HNF4-alpha(Phospho Ser313) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HNF4-alpha protein phosphorylated at Serine 313. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eHNF4-alpha, also known as Hepatocyte Nuclear Factor 4-alpha, is a transcription factor that plays a crucial role in the regulation of gene expression in various tissues, including the liver, kidney, and intestine. Phosphorylation of HNF4-alpha at Serine 313 has been shown to modulate its transcriptional activity and influence downstream gene expression.\u003cbr\u003e\u003cbr\u003eThe HNF4-alpha(Phospho Ser313) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated HNF4-alpha in complex biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for use in a variety of experimental conditions, ensuring consistent and reproducible results. The HNF4-alpha(Phospho Ser313) Polyclonal Antibody is compatible with a wide range of secondary detection systems, facilitating its integration into existing experimental workflows.\u003cbr\u003e\u003cbr\u003eResearchers and scientists studying the role of HNF4-alpha phosphorylation in gene regulation and cellular processes will greatly benefit from the use of this antibody. Its high specificity and sensitivity make it an invaluable tool for elucidating the molecular mechanisms underlying HNF4-alpha-mediated transcriptional regulation.\u003cbr\u003e\u003cbr\u003eIn summary, the HNF4-alpha(Phospho Ser313) Polyclonal Antibody is a reliable and efficient reagent for the detection and quantification of phosphorylated HNF4-alpha protein. Its exceptional performance and versatility make it an essential tool for researchers in the field of gene regulation and cellular biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546344931608,"sku":"BT-AP10099","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_072a113d-6da2-4e5f-82d6-0e528e677f36.png?v=1705680390","url":"https:\/\/danabiosci.com\/products\/new-product-578582","provider":"Dana Bioscience","version":"1.0","type":"link"}