{"product_id":"new-product-578563","title":"Histone H4(Phospho Ser47) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.\u003c\/p\u003e\n\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.\u003c\/p\u003e\n\u003cp\u003eThe Histone H4(Phospho Ser47) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Serine 47 residue on Histone H4 protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.\u003cbr\u003e\u003cbr\u003eHistone H4 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Phosphorylation of Serine 47 on Histone H4 has been implicated in various cellular processes, including DNA repair, cell cycle progression, and transcriptional regulation.\u003cbr\u003e\u003cbr\u003eThe Histone H4(Phospho Ser47) Polyclonal Antibody exhibits exceptional performance in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without compromising the quality and performance.\u003cbr\u003e\u003cbr\u003eChoose the Histone H4(Phospho Ser47) Polyclonal Antibody for your research needs and unlock the potential of studying the intricate mechanisms of histone modifications and their impact on cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546331791640,"sku":"BT-AP10048","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_125aade1-071a-45d8-83d7-ed802e898ce8.png?v=1705680281","url":"https:\/\/danabiosci.com\/products\/new-product-578563","provider":"Dana Bioscience","version":"1.0","type":"link"}