{"product_id":"new-product-578554","title":"Histone H3 (Tri-Methyl-K5) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3 (Tri-Methyl-K5) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H3 protein modifications. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. The tri-methylation of lysine 5 (K5) on histone H3 is an important post-translational modification that has been implicated in various biological processes, including transcriptional activation and chromatin remodeling.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe Histone H3 (Tri-Methyl-K5) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient size and format, allowing for easy handling and storage.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the Histone H3 (Tri-Methyl-K5) Polyclonal Antibody is an indispensable tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546323206424,"sku":"BT-AP10017","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2c06c139-ce49-4538-812f-04a03bc33077.png?v=1705680229","url":"https:\/\/danabiosci.com\/products\/new-product-578554","provider":"Dana Bioscience","version":"1.0","type":"link"}