{"product_id":"new-product-578551","title":"Histone H3(Phospho Thr6) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3(Phospho Thr6) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of phosphorylated Histone H3 at threonine 6 residue. This antibody is produced using advanced immunization techniques and exhibits excellent affinity and selectivity towards the phosphorylated form of Histone H3. \u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Phosphorylation of Histone H3 at threonine 6 has been implicated in various cellular processes, including cell cycle progression, DNA repair, and transcriptional activation. Therefore, the detection and quantification of phosphorylated Histone H3 at threonine 6 residue are of great importance in understanding the underlying molecular mechanisms involved in these processes.\u003cbr\u003e\u003cbr\u003eThe Histone H3(Phospho Thr6) Polyclonal Antibody is rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Histone H3 and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use in various applications. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins. The Histone H3(Phospho Thr6) Polyclonal Antibody is provided in a convenient size and concentration, allowing for cost-effective and efficient experiments.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H3(Phospho Thr6) Polyclonal Antibody is a valuable tool for researchers studying the role of phosphorylated Histone H3 at threonine 6 residue in cellular processes. Its high specificity, sensitivity, and versatility make it an essential component in the field of epigenetics and chromatin biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546322485528,"sku":"BT-AP10008","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_7db886ee-890f-4c6c-ad6e-c6b86a64809f.png?v=1705680215","url":"https:\/\/danabiosci.com\/products\/new-product-578551","provider":"Dana Bioscience","version":"1.0","type":"link"}