{"product_id":"new-product-578545","title":"Histone H3(Phospho Thr11) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H3(Phospho Thr11) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Histone H3 at Thr11 residue. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen.\u003cbr\u003e\u003cbr\u003eHistone H3 is a crucial protein involved in chromatin structure and gene regulation. Phosphorylation of Histone H3 at Thr11 has been implicated in various cellular processes, including DNA repair, cell cycle progression, and transcriptional activation. Therefore, the detection and quantification of phosphorylated Histone H3 at Thr11 is of great importance in understanding these biological processes.\u003cbr\u003e\u003cbr\u003eThe Histone H3(Phospho Thr11) Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness without compromising on quality. Each batch of the Histone H3(Phospho Thr11) Polyclonal Antibody undergoes rigorous quality control procedures to guarantee consistent performance and batch-to-batch reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H3(Phospho Thr11) Polyclonal Antibody is a valuable tool for researchers studying the role of phosphorylated Histone H3 at Thr11 in various biological processes. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate and precise detection and analysis.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546313441560,"sku":"BT-AP10002","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_be4eb253-c787-4682-82d8-c68e6e239826.png?v=1705680164","url":"https:\/\/danabiosci.com\/products\/new-product-578545","provider":"Dana Bioscience","version":"1.0","type":"link"}