{"product_id":"new-product-578533","title":"Histone H2B(Phospho Ser14) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis\/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2B(Phospho Ser14) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated serine 14 residue on histone H2B. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eHistone H2B is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. Phosphorylation of serine 14 on histone H2B has been implicated in various cellular processes, including transcriptional activation, DNA repair, and cell cycle progression. Therefore, the ability to accurately detect and quantify this phosphorylation event is of utmost importance in understanding the underlying mechanisms of these biological processes.\u003cbr\u003e\u003cbr\u003eThe Histone H2B(Phospho Ser14) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of phosphorylated serine 14 on histone H2B. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its versatility and reliability across different applications.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody is produced using high-quality materials and state-of-the-art manufacturing processes, ensuring batch-to-batch consistency and reproducibility. It is supplied in a convenient format, allowing for easy handling and storage.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H2B(Phospho Ser14) Polyclonal Antibody is a valuable tool for researchers studying histone modifications and their role in cellular processes. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset in the field of epigenetics and chromatin biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546305446168,"sku":"BT-AP09952","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a27717e1-bc6a-4654-9c91-15495e787bee.png?v=1705680099","url":"https:\/\/danabiosci.com\/products\/new-product-578533","provider":"Dana Bioscience","version":"1.0","type":"link"}