{"product_id":"new-product-578531","title":"Histone H2B (Acetyl Lys21) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis\/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2B (Acetyl Lys21) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of acetylated Lysine 21 on Histone H2B. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target antigen. \u003cbr\u003e\u003cbr\u003eHistone H2B is a crucial component of the nucleosome, playing a vital role in chromatin structure and gene regulation. Acetylation of Lysine 21 on Histone H2B has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the ability to accurately detect and quantify acetylated Lysine 21 is of utmost importance in understanding the intricate mechanisms of gene expression and chromatin remodeling.\u003cbr\u003e\u003cbr\u003eThe Histone H2B (Acetyl Lys21) Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results. \u003cbr\u003e\u003cbr\u003eWith its superior quality and performance, the Histone H2B (Acetyl Lys21) Polyclonal Antibody is an indispensable tool for researchers and scientists studying epigenetics, chromatin biology, and gene regulation. Its application in various experimental techniques enables a comprehensive understanding of the role of acetylated Lysine 21 on Histone H2B in cellular processes and disease development.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546303611160,"sku":"BT-AP09944","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_6a96e886-00f1-43c4-afd8-779dd1bcc2b3.png?v=1705680086","url":"https:\/\/danabiosci.com\/products\/new-product-578531","provider":"Dana Bioscience","version":"1.0","type":"link"}