{"product_id":"new-product-578527","title":"Histone H2A.X(Phospho Tyr142) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2A.X(Phospho Tyr142) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of phosphorylated Histone H2A.X at Tyr142. This antibody is produced using high-quality materials and advanced techniques to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eHistone H2A.X is a variant of the histone H2A protein family and plays a crucial role in DNA damage response and repair. Phosphorylation of Histone H2A.X at Tyr142 is a key event in the cellular response to DNA double-strand breaks, making it an important marker for DNA damage and repair studies.\u003cbr\u003e\u003cbr\u003eThe Histone H2A.X(Phospho Tyr142) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Histone H2A.X and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term use to maintain its stability and activity.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H2A.X(Phospho Tyr142) Polyclonal Antibody is a valuable tool for researchers studying DNA damage and repair processes. Its high specificity, sensitivity, and reliability make it an essential component in various molecular biology and cell biology studies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546300563736,"sku":"BT-AP09931","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e6ccadc0-9c87-4c48-b3ed-6d0f77031c53.png?v=1705680061","url":"https:\/\/danabiosci.com\/products\/new-product-578527","provider":"Dana Bioscience","version":"1.0","type":"link"}