{"product_id":"new-product-578524","title":"Histone H2A.X(Phospho Ser139) Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2A.X(Phospho Ser139) Polyclonal Antibody is a highly specific and sensitive antibody that has been designed for the detection of phosphorylated Histone H2A.X at Ser139. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Histone H2A.X(Phospho Ser139) Polyclonal Antibody is an essential tool for researchers studying DNA damage and repair mechanisms. It is particularly useful for investigating the role of Histone H2A.X in the DNA damage response, as well as for monitoring the efficacy of DNA-damaging agents in cancer therapy.\u003cbr\u003e\u003cbr\u003eThis antibody has been rigorously tested to ensure its specificity and sensitivity, and it has been shown to produce reliable and reproducible results. It is also highly versatile, with the ability to detect Histone H2A.X in a wide range of species and tissue types.\u003cbr\u003e\u003cbr\u003eOverall, the Histone H2A.X(Phospho Ser139) Polyclonal Antibody is an excellent choice for researchers looking to investigate the role of Histone H2A.X in DNA damage and repair mechanisms. Its high specificity, sensitivity, and versatility make it an essential tool for any laboratory studying these important biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546298925336,"sku":"BT-AP09928","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_8ae0ce4b-0e86-4160-b955-bbb9044e88c5.png?v=1705680048","url":"https:\/\/danabiosci.com\/products\/new-product-578524","provider":"Dana Bioscience","version":"1.0","type":"link"}