{"product_id":"new-product-578475","title":"HBEGF Polyclonal Antibody","description":"\u003cp\u003eMay be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.,PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).,PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active.,Contains 1 EGF-like domain.,subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.,\u003c\/p\u003e\n\u003cp\u003eThe HBEGF Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HBEGF protein in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eHBEGF, also known as Heparin-binding EGF-like growth factor, is a member of the epidermal growth factor (EGF) family. It plays a crucial role in various physiological and pathological processes, including cell proliferation, differentiation, and tissue repair. The HBEGF Polyclonal Antibody recognizes the full-length HBEGF protein as well as its cleaved forms, making it an ideal tool for studying the proteolytic processing of HBEGF.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. The HBEGF Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and serum.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, the HBEGF Polyclonal Antibody is an indispensable tool for researchers studying the role of HBEGF in various biological processes. Its reliable performance and versatility make it suitable for both basic research and clinical applications. Order your HBEGF Polyclonal Antibody today and unlock new insights into the intricate mechanisms of HBEGF signaling.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546268156184,"sku":"BT-AP09826","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e6e3bb42-4f0c-47ee-9639-edcd78d4d32f.png?v=1705679747","url":"https:\/\/danabiosci.com\/products\/new-product-578475","provider":"Dana Bioscience","version":"1.0","type":"link"}