{"product_id":"new-product-578428","title":"GRK 2(Phospho Ser685) Polyclonal Antibody","description":"\u003cp\u003eThe product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.\u003c\/p\u003e\n\u003cp\u003eThe GRK 2(Phospho Ser685) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GRK 2 protein phosphorylated at Ser685. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eGRK 2, also known as G protein-coupled receptor kinase 2, plays a crucial role in regulating the desensitization and internalization of G protein-coupled receptors (GPCRs). Phosphorylation of GRK 2 at Ser685 has been implicated in various cellular processes, including receptor signaling, cellular migration, and cardiac function.\u003cbr\u003e\u003cbr\u003eThe GRK 2(Phospho Ser685) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated GRK 2 protein in complex biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The GRK 2(Phospho Ser685) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.\u003cbr\u003e\u003cbr\u003eChoose the GRK 2(Phospho Ser685) Polyclonal Antibody for its exceptional performance, reliability, and versatility. It is an indispensable tool for studying the role of GRK 2 phosphorylation in various biological processes and holds great potential for advancing our understanding of GPCR signaling pathways.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546246234392,"sku":"BT-AP15789","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4fe2e855-ec5e-406d-9fb0-2a5ddbf91ba4.png?v=1705679524","url":"https:\/\/danabiosci.com\/products\/new-product-578428","provider":"Dana Bioscience","version":"1.0","type":"link"}