{"product_id":"new-product-578327","title":"GFRA2 Polyclonal Antibody","description":"\u003cp\u003eGlial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe GFRA2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GFRA2 protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of neuroscience and developmental biology.\u003cbr\u003e\u003cbr\u003eThe GFRA2 protein, also known as GDNF family receptor alpha 2, plays a crucial role in the development and maintenance of the nervous system. It is a transmembrane receptor that binds to glial cell line-derived neurotrophic factor (GDNF) and mediates its signaling pathway. GFRA2 is primarily expressed in the central and peripheral nervous systems, where it regulates neuronal survival, differentiation, and axon guidance.\u003cbr\u003e\u003cbr\u003eThe GFRA2 Polyclonal Antibody has been produced using high-quality immunogens and advanced immunization techniques, ensuring its specificity and affinity towards the target protein. It has been rigorously tested in various experimental conditions, including Western blotting, immunohistochemistry, and immunofluorescence, and has consistently demonstrated excellent performance.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. It is suitable for use in a wide range of species, including human, mouse, rat, and other mammalian species. The GFRA2 Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling.\u003cbr\u003e\u003cbr\u003eIn summary, the GFRA2 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of GFRA2 protein expression. Its exceptional sensitivity and specificity, along with its versatility in various experimental techniques, make it an invaluable asset for researchers studying the intricate mechanisms of the nervous system and its development.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546173325592,"sku":"BT-AP09477","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d966b82c-6025-4088-b00a-4012e7ea7c2c.png?v=1705678904","url":"https:\/\/danabiosci.com\/products\/new-product-578327","provider":"Dana Bioscience","version":"1.0","type":"link"}