{"product_id":"new-product-578209","title":"Flg\/Bek(Phospho Tyr463\/466) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,\u003c\/p\u003e\n\u003cp\u003eThe Flg\/Bek (Phospho Tyr463\/466) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Flg\/Bek protein phosphorylation at Tyr463 and Tyr466 residues. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe Flg\/Bek protein, also known as fibroblast growth factor receptor-like 1 (FGFRL1), plays a crucial role in various cellular processes, including cell proliferation, differentiation, and migration. Phosphorylation of specific tyrosine residues within the Flg\/Bek protein is known to regulate its activity and downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of Flg\/Bek phosphorylation in diverse biological samples.\u003cbr\u003e\u003cbr\u003eThe Flg\/Bek (Phospho Tyr463\/466) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is optimized for use in both research and diagnostic settings, facilitating comprehensive investigations into the role of Flg\/Bek phosphorylation in various physiological and pathological conditions.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance characteristics and broad applicability, the Flg\/Bek (Phospho Tyr463\/466) Polyclonal Antibody is an indispensable tool for researchers and clinicians alike. Its reliable and accurate detection of Flg\/Bek phosphorylation will contribute to a deeper understanding of cellular signaling pathways and aid in the development of novel therapeutic strategies targeting this important protein.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546096189720,"sku":"BT-AP15618","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4f68c600-f956-49e4-81bf-e706fc233461.png?v=1705678248","url":"https:\/\/danabiosci.com\/products\/new-product-578209","provider":"Dana Bioscience","version":"1.0","type":"link"}