{"product_id":"new-product-578082","title":"EpoR(Phospho Tyr426) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras\/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe EpoR(Phospho Tyr426) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the phosphorylated form of the Erythropoietin Receptor (EpoR) at Tyr426 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the phosphorylated EpoR.\u003cbr\u003e\u003cbr\u003eThe EpoR(Phospho Tyr426) Polyclonal Antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It has been extensively validated for its performance in detecting the phosphorylated EpoR in a wide range of samples, including cell lysates, tissue extracts, and biological fluids.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity and specificity, this antibody enables researchers to investigate the activation status of the EpoR signaling pathway, which plays a crucial role in erythropoiesis and hematopoiesis. By targeting the phosphorylated Tyr426 residue, this antibody allows for the precise analysis of EpoR activation and downstream signaling events.\u003cbr\u003e\u003cbr\u003eThe EpoR(Phospho Tyr426) Polyclonal Antibody is manufactured under strict quality control standards to ensure consistent and reliable results. It is supplied as a liquid formulation, ready for immediate use, and is compatible with various detection systems and experimental protocols.\u003cbr\u003e\u003cbr\u003eIn summary, the EpoR(Phospho Tyr426) Polyclonal Antibody is a valuable tool for researchers studying the EpoR signaling pathway and its involvement in erythropoiesis and hematopoiesis. Its high specificity, sensitivity, and versatility make it an essential component in the investigation of EpoR activation and downstream signaling events.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47546007879960,"sku":"BT-AP15445","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_864ed2ca-3964-44c0-9aaa-b3d0b7981ddd.png?v=1705677529","url":"https:\/\/danabiosci.com\/products\/new-product-578082","provider":"Dana Bioscience","version":"1.0","type":"link"}