{"product_id":"new-product-578051","title":"ENaC beta(Phospho Thr615) Polyclonal Antibody","description":"\u003cp\u003eNonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.\u003c\/p\u003e\n\u003cp\u003eThe ENaC beta(Phospho Thr615) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of ENaC beta protein phosphorylated at threonine 615. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eENaC beta, also known as epithelial sodium channel beta subunit, plays a crucial role in sodium reabsorption in the kidney and lung epithelia. Phosphorylation of ENaC beta at threonine 615 has been implicated in the regulation of its activity and function. Therefore, the ability to accurately measure the phosphorylation status of ENaC beta is of great importance in understanding its physiological and pathological roles.\u003cbr\u003e\u003cbr\u003eThe ENaC beta(Phospho Thr615) Polyclonal Antibody exhibits high specificity towards the phosphorylated form of ENaC beta at threonine 615, with minimal cross-reactivity to non-phosphorylated ENaC beta or other related proteins. This specificity ensures accurate and reliable results, allowing for precise quantification of ENaC beta phosphorylation levels.\u003cbr\u003e\u003cbr\u003eIn addition to its specificity, this antibody demonstrates exceptional sensitivity, enabling the detection of low levels of phosphorylated ENaC beta. This sensitivity is crucial for studying subtle changes in ENaC beta phosphorylation under different experimental conditions or disease states.\u003cbr\u003e\u003cbr\u003eThe ENaC beta(Phospho Thr615) Polyclonal Antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.\u003cbr\u003e\u003cbr\u003eOverall, the ENaC beta(Phospho Thr615) Polyclonal Antibody is a valuable tool for researchers studying the role of ENaC beta phosphorylation in various physiological and pathological processes. Its high specificity, sensitivity, and versatility make it an essential component of any study aiming to elucidate the molecular mechanisms underlying sodium reabsorption and related disorders.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545990676760,"sku":"BT-AP15399","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_30b94b82-5081-4d6e-a56f-c0db3194449e.png?v=1705677362","url":"https:\/\/danabiosci.com\/products\/new-product-578051","provider":"Dana Bioscience","version":"1.0","type":"link"}