{"product_id":"new-product-578035","title":"eIF4G(Phospho Ser1148) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.\u003c\/p\u003e\n\u003cp\u003eThe eIF4G(Phospho Ser1148) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of eIF4G protein phosphorylated at Ser1148. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe eIF4G protein plays a crucial role in the initiation of protein synthesis and is regulated by various post-translational modifications, including phosphorylation. Phosphorylation at Ser1148 has been implicated in the regulation of eIF4G function and its involvement in cellular processes such as cell growth, proliferation, and differentiation.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated eIF4G and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe eIF4G(Phospho Ser1148) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended for use in both research and clinical settings, providing valuable insights into the role of eIF4G phosphorylation in various biological processes.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the eIF4G(Phospho Ser1148) Polyclonal Antibody is an indispensable tool for researchers and scientists studying protein synthesis, cellular signaling, and related fields.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545981960472,"sku":"BT-AP15388","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_c332d507-5830-4c6d-8c9c-85758e6ddd4a.png?v=1705677271","url":"https:\/\/danabiosci.com\/products\/new-product-578035","provider":"Dana Bioscience","version":"1.0","type":"link"}