{"product_id":"new-product-577945","title":"Doublecortin(Phospho Ser339) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia (\"double cortex\" syndrome) in females and lissencephaly (\"smooth brain\u0026amp;quo\u003c\/p\u003e\n\u003cp\u003eThe Doublecortin(Phospho Ser339) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Doublecortin protein phosphorylated at Serine 339. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.\u003cbr\u003e\u003cbr\u003eDoublecortin is a protein that plays a crucial role in neuronal migration and differentiation during brain development. Phosphorylation of Doublecortin at Serine 339 has been implicated in its regulation and function. Therefore, the Doublecortin(Phospho Ser339) Polyclonal Antibody is an invaluable tool for researchers studying neurodevelopmental processes and related disorders.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits exceptional sensitivity and specificity, enabling accurate detection of Doublecortin phosphorylated at Serine 339 in various experimental settings. It has been extensively validated for use in immunohistochemistry, immunofluorescence, and Western blotting applications, providing reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThe Doublecortin(Phospho Ser339) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is also compatible with a wide range of secondary detection systems, allowing for flexibility in experimental design.\u003cbr\u003e\u003cbr\u003eIn summary, the Doublecortin(Phospho Ser339) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Doublecortin protein phosphorylated at Serine 339. Its exceptional sensitivity, specificity, and compatibility with various experimental techniques make it an essential reagent for researchers investigating neurodevelopmental processes and related disorders.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545935069464,"sku":"BT-AP08596","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_8766f855-f7b7-4060-8a54-ddb1b5fdf3b6.png?v=1705676786","url":"https:\/\/danabiosci.com\/products\/new-product-577945","provider":"Dana Bioscience","version":"1.0","type":"link"}