{"product_id":"new-product-577885","title":"DHB1 Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases\/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has\u003c\/p\u003e\n\u003cp\u003eThe DHB1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of DHB1 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the DHB1 protein. It has been extensively validated for its specificity and sensitivity, ensuring accurate and reproducible results.\u003cbr\u003e\u003cbr\u003eThe DHB1 Polyclonal Antibody exhibits exceptional affinity towards the DHB1 protein, enabling its efficient detection in Western blotting, immunohistochemistry, and immunofluorescence applications. It recognizes both the native and denatured forms of the DHB1 protein, making it suitable for a wide range of experimental techniques.\u003cbr\u003e\u003cbr\u003eWith its superior performance, the DHB1 Polyclonal Antibody offers researchers a valuable tool for studying the function and regulation of the DHB1 protein in various biological processes. Its high specificity and sensitivity make it an ideal choice for investigating DHB1 protein expression in normal and disease conditions.\u003cbr\u003e\u003cbr\u003eThe DHB1 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effective and efficient experiments. Each batch of the antibody undergoes rigorous quality control tests to guarantee consistent performance and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the DHB1 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of DHB1 protein expression. Its exceptional affinity, versatility, and consistent performance make it an indispensable asset for researchers in the field of molecular biology and biomedical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545895223576,"sku":"BT-AP15226","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d254f4a6-3979-40a6-8981-fec0bab03a49.png?v=1705676408","url":"https:\/\/danabiosci.com\/products\/new-product-577885","provider":"Dana Bioscience","version":"1.0","type":"link"}