{"product_id":"new-product-577710","title":"Cortactin(Phospho Tyr421) Polyclonal Antibody","description":"\u003cp\u003eThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.\u003c\/p\u003e\n\u003cp\u003eThe Cortactin(Phospho Tyr421) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Cortactin protein phosphorylated at Tyr421. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eCortactin is a cytoskeletal protein that plays a crucial role in cell migration, adhesion, and invasion. Phosphorylation of Cortactin at Tyr421 has been implicated in various cellular processes, including actin polymerization, cell motility, and cancer metastasis. Therefore, the ability to accurately detect and quantify Cortactin phosphorylation at Tyr421 is of great importance in understanding the underlying mechanisms of these processes.\u003cbr\u003e\u003cbr\u003eThe Cortactin(Phospho Tyr421) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of Cortactin phosphorylation at Tyr421. It has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. This antibody demonstrates minimal cross-reactivity with non-phosphorylated Cortactin and other related proteins, ensuring reliable and accurate results.\u003cbr\u003e\u003cbr\u003eFurthermore, the Cortactin(Phospho Tyr421) Polyclonal Antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and high reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. The antibody is provided in a convenient format, allowing for easy storage and handling.\u003cbr\u003e\u003cbr\u003eIn summary, the Cortactin(Phospho Tyr421) Polyclonal Antibody is a valuable tool for researchers studying Cortactin phosphorylation at Tyr421. Its exceptional specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications, including basic research, drug discovery, and clinical diagnostics.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545796624664,"sku":"BT-AP08009","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4a7f58c1-b2a7-4cee-a3f4-f129a4c9a316.png?v=1705675490","url":"https:\/\/danabiosci.com\/products\/new-product-577710","provider":"Dana Bioscience","version":"1.0","type":"link"}