COL13A1 Polyclonal Antibody

COL13A1 encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined.

The COL13A1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of COL13A1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human COL13A1 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The COL13A1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the COL13A1 protein in human, mouse, and rat tissues, with no cross-reactivity with other related proteins.

This antibody is an essential tool for researchers studying the role of COL13A1 in various biological processes, including cell adhesion, migration, and invasion. It can also be used for diagnostic purposes in the detection of COL13A1 expression in various diseases, including cancer.

In summary, the COL13A1 Polyclonal Antibody is a reliable and high-quality antibody that provides accurate and reproducible results in various applications. Its specificity and sensitivity make it an ideal tool for researchers and clinicians studying the role of COL13A1 in various biological processes and diseases.