{"product_id":"new-product-577680","title":"CO5 Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe CO5 Polyclonal Antibody is a highly specific and reliable tool for various research applications. This antibody is produced by immunizing animals with a CO5 antigen, resulting in a polyclonal antibody that exhibits exceptional affinity and sensitivity towards CO5. \u003cbr\u003e\u003cbr\u003eWith its superior specificity, the CO5 Polyclonal Antibody enables accurate detection and quantification of CO5 in a wide range of samples. It has been extensively validated for use in immunohistochemistry, immunofluorescence, Western blotting, and other immunoassays. \u003cbr\u003e\u003cbr\u003eThe CO5 Polyclonal Antibody offers exceptional performance, delivering consistent and reproducible results. Its high affinity ensures minimal background noise, allowing for precise and reliable data interpretation. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is available in various sizes to accommodate different experimental needs. \u003cbr\u003e\u003cbr\u003eChoose the CO5 Polyclonal Antibody for your research needs and experience the confidence of working with a high-quality and reliable tool that guarantees accurate and reproducible results.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545782141208,"sku":"BT-AP07922","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_88f52bc8-ff03-471b-b359-b5dc7f78a82b.png?v=1705675336","url":"https:\/\/danabiosci.com\/products\/new-product-577680","provider":"Dana Bioscience","version":"1.0","type":"link"}