CLD22 Polyclonal Antibody

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

The CLD22 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CLD22 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique epitope of the CLD22 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for various applications in research and diagnostics.

The CLD22 Polyclonal Antibody has been extensively validated for its performance in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect CLD22 protein in a wide range of species, including human, mouse, rat, and others. The antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. This ensures high purity and minimal cross-reactivity with other proteins.

The CLD22 Polyclonal Antibody is a valuable tool for researchers studying the role of CLD22 protein in various biological processes, including cell adhesion, migration, and signaling. It can also be used for the development of diagnostic assays for diseases associated with CLD22 protein dysregulation. With its high specificity and sensitivity, this antibody is a reliable and effective reagent for a wide range of applications in life sciences research.