{"product_id":"new-product-577466","title":"CD218b Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.\u003c\/p\u003e\n\u003cp\u003eThe CD218b Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of CD218b protein expression. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards CD218b. \u003cbr\u003e\u003cbr\u003eCD218b, also known as the Interleukin-18 receptor beta chain, plays a crucial role in the immune response by mediating the signaling of Interleukin-18 (IL-18). IL-18 is a pro-inflammatory cytokine that is involved in various physiological and pathological processes, including immune regulation, inflammation, and host defense against infections. \u003cbr\u003e\u003cbr\u003eThe CD218b Polyclonal Antibody is validated for multiple applications, including Western blotting, immunohistochemistry, and flow cytometry. It exhibits excellent performance in detecting CD218b protein expression in various sample types, such as cell lysates, tissue sections, and whole blood. \u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, this antibody enables accurate and reliable quantification of CD218b expression levels, facilitating research in immunology, inflammation, and related fields. Its versatility and robustness make it an indispensable tool for scientists and researchers seeking to unravel the intricate mechanisms underlying immune responses and inflammatory diseases. \u003cbr\u003e\u003cbr\u003eThe CD218b Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and minimizing experimental variability. It is available in different sizes to accommodate various experimental needs. Each batch of antibody undergoes stringent quality control measures to guarantee consistent performance and reproducibility. \u003cbr\u003e\u003cbr\u003eIn summary, the CD218b Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of CD218b protein expression. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers in the field of immunology and inflammation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545632424216,"sku":"BT-AP14803","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a32b9d51-48c0-4e5c-b3dd-a72136f44de2.png?v=1705674150","url":"https:\/\/danabiosci.com\/products\/new-product-577466","provider":"Dana Bioscience","version":"1.0","type":"link"}