c-Abl Rabbit Polyclonal Antibody

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.

The c-Abl Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of c-Abl protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional performance and reliability.

The c-Abl Rabbit Polyclonal Antibody exhibits excellent affinity and specificity towards the c-Abl protein, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to deliver consistent and reproducible results.

With its superior sensitivity, this antibody allows for the detection of even low levels of c-Abl protein, enabling accurate quantification and analysis. Its robust performance ensures minimal background noise, resulting in clear and reliable data interpretation.

The c-Abl Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, making it easy to incorporate into your experimental workflow. It is provided in a liquid form, eliminating the need for reconstitution, and is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the c-Abl Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of c-Abl protein expression. Its exceptional sensitivity, robust performance, and compatibility with various applications and sample types make it an invaluable asset for researchers in the field of molecular biology and beyond.