{"product_id":"new-product-577244","title":"Bax Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.\u003c\/p\u003e\n\u003cp\u003eThe Bax Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Bax protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Bax protein. The resulting polyclonal antibody is purified using protein A affinity chromatography and is validated for its specificity and sensitivity by various immunoassays.\u003cbr\u003e\u003cbr\u003eThe Bax protein is a member of the Bcl-2 family of proteins that plays a crucial role in regulating apoptosis or programmed cell death. The overexpression of Bax protein has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, the detection of Bax protein levels is essential for understanding the underlying mechanisms of these diseases and developing effective therapeutic strategies.\u003c\/p\u003e\n\u003cp\u003eThe Bax Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Bax protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Bax protein. The resulting polyclonal antibody is purified using protein A affinity chromatography and is validated for its specificity and sensitivity by various immunoassays.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Bax protein is a member of the Bcl-2 family of proteins that plays a crucial role in regulating apoptosis or programmed cell death. The overexpression of Bax protein has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, the detection of Bax protein levels is essential for understanding the underlying mechanisms of these diseases and developing effective therapeutic strategies.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe Bax Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody has been tested and validated for its performance in detecting Bax protein in human, mouse, and rat tissues. The high specificity and sensitivity of this antibody make it an ideal tool for researchers and clinicians working in the fields of cancer biology, neuroscience, and cardiovascular research.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eIn summary, the Bax Polyclonal Antibody is a reliable and effective tool for the detection of Bax protein in various biological samples. Its high specificity and sensitivity make it an essential reagent for researchers and clinicians working in the fields of cancer biology, neuroscience, and cardiovascular research.\u003cbr\u003e\u003cbr\u003eThe Bax Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody has been tested and validated for its performance in detecting Bax protein in human, mouse, and rat tissues. The high specificity and sensitivity of this antibody make it an ideal tool for researchers and clinicians working in the fields of cancer biology, neuroscience, and cardiovascular research.\u003cbr\u003e\u003cbr\u003eIn summary, the Bax Polyclonal Antibody is a reliable and effective tool for the detection of Bax protein in various biological samples. Its high specificity and sensitivity make it an essential reagent for researchers and clinicians working in the fields of cancer biology, neuroscience, and cardiovascular research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545488933144,"sku":"BT-AP06694","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_39c941bc-19b6-4c82-ae76-07f86ad8bcc2.png?v=1705672892","url":"https:\/\/danabiosci.com\/products\/new-product-577244","provider":"Dana Bioscience","version":"1.0","type":"link"}