AT1A3 Polyclonal Antibody

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The AT1A3 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of AT1A3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human AT1A3 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for a wide range of applications in research and diagnostics.

The AT1A3 Polyclonal Antibody has been extensively validated for its performance in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect endogenous AT1A3 protein in human and mouse tissues with high sensitivity and specificity. The antibody is also suitable for use in other species, including rat and bovine.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. The purified antibody is provided in a liquid form, which can be easily diluted and used in various immunoassays. The antibody is also available in different formats, including unconjugated and conjugated forms with various labels, such as HRP, biotin, and FITC.

In summary, the AT1A3 Polyclonal Antibody is a highly specific and sensitive immunological reagent that can be used for the detection and quantification of AT1A3 protein in various biological samples. Its high affinity and specificity make it an ideal tool for a wide range of applications in research and diagnostics.