AR Polyclonal Antibody

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoform

Introducing the AR Polyclonal Antibody by BT Lab, a cutting-edge product meticulously designed to cater to the diverse needs of the scientific community. Developed by Dana Biosciences, a renowned name in the field of biotechnology, this antibody offers unparalleled specificity and sensitivity, making it an indispensable tool for researchers and scientists alike.

The AR Polyclonal Antibody is meticulously crafted using state-of-the-art techniques, ensuring exceptional quality and reliability. With its high affinity and selectivity towards the androgen receptor (AR), this antibody enables precise detection and analysis of AR expression in various biological samples.

This antibody's exceptional performance is attributed to its polyclonal nature, which allows for enhanced recognition of multiple epitopes on the AR protein. This feature ensures accurate and reliable results, even in complex experimental setups. Moreover, the AR Polyclonal Antibody exhibits minimal cross-reactivity, guaranteeing specificity and reducing the chances of false-positive or false-negative outcomes.

The AR Polyclonal Antibody by BT Lab is compatible with a wide range of applications, including immunohistochemistry (IHC), western blotting, and immunofluorescence. Its versatility enables researchers to explore AR expression patterns in diverse tissues and cell types, facilitating comprehensive investigations into the role of AR in various physiological and pathological processes.

To ensure utmost convenience, this antibody is provided in a ready-to-use format, eliminating the need for time-consuming preparations. Its long shelf life and stability further enhance its usability, allowing for consistent and reproducible results over an extended period.

In summary, the AR Polyclonal Antibody by BT Lab is a superior product that combines cutting-edge technology, exceptional specificity, and versatility. With its unrivaled performance, this antibody empowers researchers to unravel the intricate mechanisms underlying AR-mediated processes, paving the way for groundbreaking discoveries in the field of biomedicine.