{"product_id":"new-product-577062","title":"ALK(Phospho-Tyr1586) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)\/EML4 (chromosome 2), ALK\/RANBP2 (chromosome 2), ALK\/ATIC (chromosome 2), ALK\/TFG (chromosome 3), ALK\/NPM1 (chromosome 5), ALK\/SQSTM1 (chromosome\u003c\/p\u003e\n\u003cp\u003eThe ALK(Phospho-Tyr1586) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ALK protein phosphorylated at tyrosine 1586. This antibody is produced using high-quality polyclonal antibodies that have been rigorously tested for specificity and sensitivity. The ALK(Phospho-Tyr1586) Polyclonal Antibody is ideal for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry. This antibody is suitable for use in both research and diagnostic applications and has been validated for use in human, mouse, and rat samples. With its high specificity and sensitivity, the ALK(Phospho-Tyr1586) Polyclonal Antibody is an essential tool for researchers and clinicians studying the role of ALK in cancer and other diseases.\u003c\/p\u003e\n\u003cp\u003eThe ALK(PHOSPHO-TYR1586) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of ALK protein phosphorylated at tyrosine 1586. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe ALK(PHOSPHO-TYR1586) Polyclonal Antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It has been extensively validated for its performance in detecting ALK phosphorylation at tyrosine 1586 in a wide range of sample types, including cell lysates and tissue sections.\u003cbr\u003e\u003cbr\u003eWith its exceptional sensitivity and specificity, this antibody enables researchers to accurately study the phosphorylation status of ALK at tyrosine 1586, providing valuable insights into the activation and regulation of this important protein. Its reliable performance ensures consistent and reproducible results, making it an indispensable tool for any researcher studying ALK signaling pathways.\u003cbr\u003e\u003cbr\u003eThe ALK(PHOSPHO-TYR1586) Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, ensuring stability and ease of use. Each batch of antibody undergoes rigorous quality control testing to ensure consistent performance and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the ALK(PHOSPHO-TYR1586) Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and analysis of ALK protein phosphorylated at tyrosine 1586. Its exceptional performance, reliability, and ease of use make it an ideal choice for researchers investigating ALK signaling pathways and related biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545381781784,"sku":"BT-AP14180","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_00ff7ebf-e7a0-4921-8e67-20e7491c6cf4.png?v=1705671897","url":"https:\/\/danabiosci.com\/products\/new-product-577062","provider":"Dana Bioscience","version":"1.0","type":"link"}