{"product_id":"new-product-576992","title":"Acetyl Kine Polyclonal Antibody","description":"\u003cp\u003eAcetylation of lysine| like phosphorylation of serine| threonine or tyrosine| is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A| H2B| H3| and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) .Signaling resulting in acetylation\/deacetylation of histones| transcription factors| and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity| cell growth| differentiation| and apoptosis.Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism| longevity| actin polymerization| and nuclear transport.The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases| and HDACs have become promising targets for anti-cancer drugs currently in development.\u003c\/p\u003e\n\u003cp\u003eThe Acetyl Kine Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify acetylated lysine residues in a variety of biological samples. This antibody has been extensively validated for use in a range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.\u003cbr\u003e\u003cbr\u003eThe Acetyl Kine Polyclonal Antibody is produced using state-of-the-art techniques and is of the highest quality. It has been rigorously tested to ensure that it is free from contaminants and that it provides reliable and reproducible results. This antibody is suitable for use in both research and diagnostic applications.\u003cbr\u003e\u003cbr\u003eThe Acetyl Kine Polyclonal Antibody is supplied in a convenient format that is easy to use and store. It is available in a range of sizes to suit different experimental requirements. This antibody is also compatible with a range of detection systems, making it a versatile tool for researchers and clinicians alike.\u003cbr\u003e\u003cbr\u003eOverall, the Acetyl Kine Polyclonal Antibody is a valuable tool for anyone studying acetylation in biological systems. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its quality and reliability ensure that it will provide accurate and reproducible results every time.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47545339937048,"sku":"BT-AP14070","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_9397995d-e967-4df7-b2c1-997c1c4a0041.png?v=1705671525","url":"https:\/\/danabiosci.com\/products\/new-product-576992","provider":"Dana Bioscience","version":"1.0","type":"link"}